1RI8
Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme
Summary for 1RI8
Entry DOI | 10.2210/pdb1ri8/pdb |
Descriptor | camelid ANTIBODY HEAVY CHAIN, Lysozyme C, GLYCEROL, ... (4 entities in total) |
Functional Keywords | beta sandwich, immunoglobulin fold, vhh-lysozyme complex, alpha-beta orthogonal bundle, immune system-hydrolase complex, immune system/hydrolase |
Biological source | Camelus dromedarius (Arabian camel) More |
Cellular location | Secreted: P00698 |
Total number of polymer chains | 2 |
Total formula weight | 29140.53 |
Authors | De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S. (deposition date: 2003-11-17, release date: 2005-02-01, Last modification date: 2011-07-13) |
Primary citation | De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S. Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. J.Biol.Chem., 280:14114-14121, 2005 Cited by PubMed: 15659390DOI: 10.1074/jbc.M413011200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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