1RI8

Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme

1RI8 の概要

• エントリーDOI: 10.2210/pdb1ri8/pdb
• 分子名称: camelid ANTIBODY HEAVY CHAIN, Lysozyme C, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: beta sandwich, immunoglobulin fold, vhh-lysozyme complex, alpha-beta orthogonal bundle, immune system-hydrolase complex, immune system/hydrolase
• 由来する生物種: Camelus dromedarius (Arabian camel); 詳細
• 細胞内の位置: Secreted: P00698
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29140.53

構造登録者

De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S. (登録日: 2003-11-17, 公開日: 2005-02-01, 最終更新日: 2011-07-13)

• 主引用文献: De Genst, E.,Silence, K.,Ghahroudi, M.A.,Decanniere, K.,Loris, R.,Kinne, J.,Wyns, L.,Muyldermans, S.; Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.; J.Biol.Chem., 280:14114-14121, 2005; PubMed: 15659390; DOI: 10.1074/jbc.M413011200

実験手法

X-RAY DIFFRACTION (1.85 Å)