1RF8

Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490

1RF8 の概要

• エントリーDOI: 10.2210/pdb1rf8/pdb
• 関連するPDBエントリー: 1AP8
• 分子名称: Eukaryotic translation initiation factor 4E, Eukaryotic initiation factor 4F subunit p150, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, ... (4 entities in total)
• 機能のキーワード: initiation factor, protein biosynthesis, translation regulation, biosynthetic protein, translation
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast); 詳細
• 細胞内の位置: Cytoplasm: P39935
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36814.36

構造登録者

Gross, J.D.,Moerke, N.J.,von der Haar, T.,Lugovskoy, A.A.,Sachs, A.B.,McCarthy, J.E.G.,Wagner, G. (登録日: 2003-11-07, 公開日: 2003-12-23, 最終更新日: 2024-03-06)

• 主引用文献: Gross, J.D.,Moerke, N.J.,von der Haar, T.,Lugovskoy, A.A.,Sachs, A.B.,McCarthy, J.E.,Wagner, G.; Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.; Cell(Cambridge,Mass.), 115:739-750, 2003; PubMed: 14675538; DOI: 10.1016/S0092-8674(03)00975-9

実験手法

SOLUTION NMR