1RD3

2.5A Structure of Anticoagulant Thrombin Variant E217K

1RD3 の概要

• エントリーDOI: 10.2210/pdb1rd3/pdb
• 分子名称: Prothrombin, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 70056.48

構造登録者

Carter, W.J.,Myles, T.,Leung, L.L.,Huntington, J.A. (登録日: 2003-11-05, 公開日: 2004-05-04, 最終更新日: 2023-08-23)

• 主引用文献: Carter, W.J.,Myles, T.,Gibbs, C.S.,Leung, L.L.,Huntington, J.A.; Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery; J.Biol.Chem., 279:26387-26394, 2004; PubMed: 15075325; DOI: 10.1074/jbc.M402364200

実験手法

X-RAY DIFFRACTION (2.5 Å)