1RCT

Crystal structure of Human purine nucleoside phosphorylase complexed with INOSINE

Summary for 1RCT

Entry DOI	10.2210/pdb1rct/pdb
Related	1M73 1PWY 1V3Q
Descriptor	Purine nucleoside phosphorylase, SULFATE ION, INOSINE, ... (4 entities in total)
Functional Keywords	purine nucleoside phosphorylase, drug design, synchrotron, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton (By similarity): P00491
Total number of polymer chains	1
Total formula weight	32610.10
Authors	Canduri, F.,dos Santos, D.M.,Silva, R.G.,Mendes, M.A.,Palma, M.S.,de Azevedo Jr., W.F.,Basso, L.A.,Santos, D.S. (deposition date: 2003-11-04, release date: 2004-01-20, Last modification date: 2023-10-25)
Primary citation	Canduri, F.,dos Santos, D.M.,Silva, R.G.,Mendes, M.A.,Basso, L.A.,Palma, M.S.,de Azevedo Jr., W.F.,Santos, D.S. Structures of human purine nucleoside phosphorylase complexed with inosine and ddI Biochem.Biophys.Res.Commun., 313:907-914, 2004 Cited by PubMed: 14706628 DOI: 10.1016/j.bbrc.2003.11.179 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation