1R7E
NMR structure of the membrane anchor domain (1-31) of the nonstructural protein 5A (NS5A) of hepatitis C virus (Minimized average structure. Sample in 100mM SDS).
1R7E の概要
エントリーDOI | 10.2210/pdb1r7e/pdb |
関連するPDBエントリー | 1R7C 1R7D 1R7F 1R7G |
NMR情報 | BMRB: 5978 |
分子名称 | Genome polyprotein (1 entity in total) |
機能のキーワード | membrane anchor domain, hcv ns5a protein, peptide., membrane protein |
細胞内の位置 | Core protein p21: Host endoplasmic reticulum membrane; Single-pass membrane protein (By similarity). Core protein p19: Virion (By similarity). Envelope glycoprotein E1: Virion membrane; Single-pass type I membrane protein (Potential). Envelope glycoprotein E2: Virion membrane; Single-pass type I membrane protein (Potential). p7: Host endoplasmic reticulum membrane; Multi-pass membrane protein. Protease NS2-3: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein. Non-structural protein 5A: Host endoplasmic reticulum membrane; Peripheral membrane protein. RNA-directed RNA polymerase: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential): P27958 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 3770.42 |
構造登録者 | Penin, F.,Brass, V.,Appel, N.,Ramboarina, S.,Montserret, R.,Ficheux, D.,Blum, H.E.,Bartenschlager, R.,Moradpour, D. (登録日: 2003-10-21, 公開日: 2004-08-10, 最終更新日: 2024-05-22) |
主引用文献 | Penin, F.,Brass, V.,Appel, N.,Ramboarina, S.,Montserret, R.,Ficheux, D.,Blum, H.E.,Bartenschlager, R.,Moradpour, D. Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A. J.Biol.Chem., 279:40835-40843, 2004 Cited by PubMed: 15247283DOI: 10.1074/jbc.M404761200 主引用文献が同じPDBエントリー |
実験手法 | SOLUTION NMR |
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