1R54

Crystal structure of the catalytic domain of human ADAM33

Summary for 1R54

Entry DOI	10.2210/pdb1r54/pdb
Related	1R55
Descriptor	ADAM 33, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
Functional Keywords	metalloprotease, asthma, adam, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type I membrane protein: Q9BZ11
Total number of polymer chains	1
Total formula weight	24168.39
Authors	Orth, P.,Reicher, P.,Wang, W.,Prosise, W.W.,Yarosh-Tomaine, T.,Hammond, G.,Xiao, L.,Mirza, U.A.,Zou, J.,Strickland, C.,Taremi, S.S. (deposition date: 2003-10-09, release date: 2004-10-12, Last modification date: 2021-10-27)
Primary citation	Orth, P.,Reichert, P.,Wang, W.,Prosise, W.W.,Yarosh-Tomaine, T.,Hammond, G.,Xiao, L.,Mirza, U.A.,Zou, J.,Strickland, C.,Taremi, S.S.,Le, H.V.,Madison, V. Crystal structre of the catalytic domain of human ADAM33 J.Mol.Biol., 335:129-137, 2004 Cited by PubMed: 14659745 DOI: 10.1016/j.jmb.2003.10.037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation