1R4L
Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)
Summary for 1R4L
Entry DOI | 10.2210/pdb1r4l/pdb |
Related | 1R42 |
Descriptor | angiotensin I converting enzyme 2, disordered segment of collectrin homology domain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | zinc metallopeptidase domain, collectrin homology domain, inhibitor bound conformation, chloride ion binding site, zinc ion binding site, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 76979.55 |
Authors | Towler, P.,Staker, B.,Prasad, S.G.,Menon, S.,Ryan, D.,Tang, J.,Parsons, T.,Fisher, M.,Williams, D.,Dales, N.A.,Patane, M.A.,Pantoliano, M.W. (deposition date: 2003-10-07, release date: 2004-02-03, Last modification date: 2023-08-23) |
Primary citation | Towler, P.,Staker, B.,Prasad, S.G.,Menon, S.,Tang, J.,Parsons, T.,Ryan, D.,Fisher, M.,Williams, D.,Dales, N.A.,Patane, M.A.,Pantoliano, M.W. ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis. J.Biol.Chem., 279:17996-18007, 2004 Cited by PubMed: 14754895DOI: 10.1074/jbc.M311191200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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