1R4E

Solution structure of the Complex Formed between a Left-Handed Wedge-Shaped Spirocyclic Molecule and Bulged DNA

1R4E の概要

• エントリーDOI: 10.2210/pdb1r4e/pdb
• 関連するPDBエントリー: 1P96
• 分子名称: 5'-D(*CP*AP*CP*GP*CP*AP*GP*TP*TP*CP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*GP*AP*TP*GP*CP*GP*TP*G)-3', SPIRO[NAPHTHALENE-2(3H),3'(10'H)-PENTALENO[1,2-B]NAPHTHALENE]-3,10'-DIONE, 2'-[(2-AMINO-2-DEOXY-B-D-GULOPYRANOSYL)OXY]-1,1',2',3'A,4,10'A-HEXAHYDRO-,(2'R,3'AS,10'AR)-(9CI) (3 entities in total)
• 機能のキーワード: wedge-shaped spirocyclic enantiomer-bulged dna complex, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8489.76

構造登録者

Hwang, G.S.,Jones, G.B.,Goldberg, I.H. (登録日: 2003-10-06, 公開日: 2004-04-27, 最終更新日: 2024-05-01)

• 主引用文献: Hwang, G.S.,Jones, G.B.,Goldberg, I.H.; Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes.; Biochemistry, 43:641-650, 2004; PubMed: 14730968; DOI: 10.1021/bi035824i

実験手法

SOLUTION NMR