1QYP

THERMOCOCCUS CELER RPB9, NMR, 25 STRUCTURES

1QYP の概要

• エントリーDOI: 10.2210/pdb1qyp/pdb
• 分子名称: RNA POLYMERASE II, ZINC ION (2 entities in total)
• 機能のキーワード: transcription, rna polymerase ii subunit, rpb9, zn ribbon, hyperthermophilic, extremophile
• 由来する生物種: Thermococcus celer
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 6707.88

構造登録者

Wang, B.,Jones, D.N.M.,Kaine, B.P.,Weiss, M.A. (登録日: 1997-08-19, 公開日: 1997-12-24, 最終更新日: 2024-05-01)

主引用文献

Wang, B.,Jones, D.N.,Kaine, B.P.,Weiss, M.A.
High-resolution structure of an archaeal zinc ribbon defines a general architectural motif in eukaryotic RNA polymerases.
Structure, 6:555-569, 1998

PubMed Abstract: Transcriptional initiation and elongation provide control points in gene expression. Eukaryotic RNA polymerase II subunit 9 (RPB9) regulates start-site selection and elongational arrest. RPB9 contains Cys4 Zn(2+)-binding motifs which are conserved in archaea and homologous to those of the general transcription factors TFIIB and TFIIS.

PubMed: 9634694
DOI: 10.1016/S0969-2126(98)00058-6

実験手法

SOLUTION NMR