1QXY
Crystal structure of S. aureus methionine aminopeptidase in complex with a ketoheterocycle 618
Summary for 1QXY
Entry DOI | 10.2210/pdb1qxy/pdb |
Related | 1QXW 1QXZ |
Descriptor | methionyl aminopeptidase, COBALT (II) ION, ACETATE ION, ... (5 entities in total) |
Functional Keywords | pita bread fold, hydrolase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 27999.41 |
Authors | Douangamath, A.,Dale, G.E.,D'Arcy, A.,Oefner, C. (deposition date: 2003-09-09, release date: 2004-03-16, Last modification date: 2024-02-14) |
Primary citation | Douangamath, A.,Dale, G.E.,D'Arcy, A.,Almstetter, M.,Eckl, R.,Frutos-Hoener, A.,Henkel, B.,Illgen, K.,Nerdinger, S.,Schulz, H.,MacSweeney, A.,Thormann, M.,Treml, A.,Pierau, S.,Wadman, S.,Oefner, C. Crystal structures of staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate. J.Med.Chem., 47:1325-1328, 2004 Cited by PubMed: 14998322DOI: 10.1021/jm034188j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.04 Å) |
Structure validation
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