1QXB

NMR structure determination of the self complementary DNA Dodecamer CGCGAATT*CGCG in which a ribose is inserted between the 3'-OH of T8 and the 5'-phosphate group of C9

1QXB の概要

• エントリーDOI: 10.2210/pdb1qxb/pdb
• 分子名称: 5'-d(CpGpCpGpApApTpTpCpGpCpG)-3', beta-D-ribofuranose (2 entities in total)
• 機能のキーワード: disaccharide nucleotide, backbone modification, b-helix, ribose, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7627.04

構造登録者

Nauwelaerts, K.,Vastmans, K.,Froeyen, M.,Kempeneers, V.,Rozenski, J.,Rosemeyer, H.,Van Aerschot, A.,Busson, R.,Efimtseva, E.,Mikhailov, S.,Lescrinier, E.,Herdewijn, P. (登録日: 2003-09-05, 公開日: 2004-02-03, 最終更新日: 2024-05-01)

• 主引用文献: Nauwelaerts, K.,Vastmans, K.,Froeyen, M.,Kempeneers, V.,Rozenski, J.,Rosemeyer, H.,Van Aerschot, A.,Busson, R.,Lacey, J.C.,Efimtseva, E.,Mikhailov, S.,Lescrinier, E.,Herdewijn, P.; Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside.; Nucleic Acids Res., 31:6758-6769, 2003; PubMed: 14627809; DOI: 10.1093/nar/gkg911

実験手法

SOLUTION NMR