1QWC
Rat neuronal nitric oxide synthase oxygenase domain in complex with W1400 inhibitor.
Summary for 1QWC
| Entry DOI | 10.2210/pdb1qwc/pdb |
| Related | 1QW4 1QW5 1QW6 |
| Descriptor | Nitric-oxide synthase, brain, ZINC ION, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total) |
| Functional Keywords | rat nnosoxy w1400 inhibitor complex, oxidoreductase |
| Biological source | Rattus norvegicus (Norway rat) |
| Cellular location | Cell membrane, sarcolemma ; Peripheral membrane protein : P29476 |
| Total number of polymer chains | 1 |
| Total formula weight | 49680.59 |
| Authors | Fedorov, R.,Hartmann, E.,Ghosh, D.K.,Schlichting, I. (deposition date: 2003-09-02, release date: 2003-12-09, Last modification date: 2024-02-14) |
| Primary citation | Fedorov, R.,Hartmann, E.,Ghosh, D.K.,Schlichting, I. Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms. J.Biol.Chem., 278:45818-45825, 2003 Cited by PubMed: 12954642DOI: 10.1074/jbc.M306030200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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