1QTY

VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR

Summary for 1QTY

Entry DOI	10.2210/pdb1qty/pdb
Related	1FLT 1QSV 1QSZ
Descriptor	VASCULAR ENDOTHELIAL GROWTH FACTOR, FMS-LIKE TYROSINE KINASE 1 (2 entities in total)
Functional Keywords	complex (growth factor-receptor), flt-1, vegf receptor, receptor tyrosine kinase, cystine knot, glycoprotein, immunoglobulin-like domain, i-set, hormone/growth factor receptor, hormone-growth factor receptor complex
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P15692 Isoform Flt1: Cell membrane; Single-pass type I membrane protein. Isoform sFlt1: Secreted: P17948
Total number of polymer chains	8
Total formula weight	93947.91
Authors	Wiesmann, C.,de Vos, A.M. (deposition date: 1999-06-29, release date: 2000-01-12, Last modification date: 2023-08-16)
Primary citation	Starovasnik, M.A.,Christinger, H.W.,Wiesmann, C.,Champe, M.A.,de Vos, A.M.,Skelton, N.J. Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states. J.Mol.Biol., 293:531-544, 1999 Cited by PubMed: 10543948 DOI: 10.1006/jmbi.1999.3134 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation