1QTY
VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR
Summary for 1QTY
Entry DOI | 10.2210/pdb1qty/pdb |
Related | 1FLT 1QSV 1QSZ |
Descriptor | VASCULAR ENDOTHELIAL GROWTH FACTOR, FMS-LIKE TYROSINE KINASE 1 (2 entities in total) |
Functional Keywords | complex (growth factor-receptor), flt-1, vegf receptor, receptor tyrosine kinase, cystine knot, glycoprotein, immunoglobulin-like domain, i-set, hormone/growth factor receptor, hormone-growth factor receptor complex |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P15692 Isoform Flt1: Cell membrane; Single-pass type I membrane protein. Isoform sFlt1: Secreted: P17948 |
Total number of polymer chains | 8 |
Total formula weight | 93947.91 |
Authors | Wiesmann, C.,de Vos, A.M. (deposition date: 1999-06-29, release date: 2000-01-12, Last modification date: 2023-08-16) |
Primary citation | Starovasnik, M.A.,Christinger, H.W.,Wiesmann, C.,Champe, M.A.,de Vos, A.M.,Skelton, N.J. Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states. J.Mol.Biol., 293:531-544, 1999 Cited by PubMed: 10543948DOI: 10.1006/jmbi.1999.3134 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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