1QTY

VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR

1QTY の概要

• エントリーDOI: 10.2210/pdb1qty/pdb
• 関連するPDBエントリー: 1FLT 1QSV 1QSZ
• 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR, FMS-LIKE TYROSINE KINASE 1 (2 entities in total)
• 機能のキーワード: complex (growth factor-receptor), flt-1, vegf receptor, receptor tyrosine kinase, cystine knot, glycoprotein, immunoglobulin-like domain, i-set, hormone/growth factor receptor, hormone-growth factor receptor complex
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P15692; Isoform Flt1: Cell membrane; Single-pass type I membrane protein. Isoform sFlt1: Secreted: P17948
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 93947.91

構造登録者

Wiesmann, C.,de Vos, A.M. (登録日: 1999-06-29, 公開日: 2000-01-12, 最終更新日: 2023-08-16)

• 主引用文献: Starovasnik, M.A.,Christinger, H.W.,Wiesmann, C.,Champe, M.A.,de Vos, A.M.,Skelton, N.J.; Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states.; J.Mol.Biol., 293:531-544, 1999; PubMed: 10543948; DOI: 10.1006/jmbi.1999.3134

実験手法

X-RAY DIFFRACTION (2.7 Å)