1QQQ
CRYSTAL STRUCTURE ANALYSIS OF SER254 MUTANT OF ESCHERICHIA COLI THYMIDYLATE SYNTHASE
Summary for 1QQQ
Entry DOI | 10.2210/pdb1qqq/pdb |
Descriptor | THYMIDYLATE SYNTHASE, SULFATE ION (3 entities in total) |
Functional Keywords | thymidylate synthase, methyltransferase, transferase |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P0A884 |
Total number of polymer chains | 1 |
Total formula weight | 31142.28 |
Authors | Fantz, C.,Shaw, D.,Jennings, W.,Forsthoefel, A.,Kitchens, M.,Phan, J.,Minor, W.,Lebioda, L.,Berger, F.G.,Spencer, H.T. (deposition date: 1999-06-07, release date: 1999-06-14, Last modification date: 2022-04-13) |
Primary citation | Fantz, C.,Shaw, D.,Jennings, W.,Forsthoefel, A.,Kitchens, M.,Phan, J.,Minor, W.,Lebioda, L.,Berger, F.G.,Spencer, H.T. Drug-resistant variants of Escherichia coli thymidylate synthase: effects of substitutions at Pro-254. Mol.Pharmacol., 57:359-366, 2000 Cited by PubMed: 10648646PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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