1QPQ

Structure of Quinolinic Acid Phosphoribosyltransferase from Mycobacterium Tuberculosis: A Potential TB Drug Target

1QPQ の概要

• エントリーDOI: 10.2210/pdb1qpq/pdb
• 分子名称: QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION, QUINOLINIC ACID, ... (4 entities in total)
• 機能のキーワード: type ii prtase, de novo nad biosynthesis, prpp, phosphoribosyl transferase, quinolinic acid, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, transferase
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 180684.27

構造登録者

Sharma, V.,Grubmeyer, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 1998-11-20, 公開日: 1998-11-25, 最終更新日: 2023-12-27)

• 主引用文献: Sharma, V.,Grubmeyer, C.,Sacchettini, J.C.; Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target.; Structure, 6:1587-1599, 1998; PubMed: 9862811; DOI: 10.1016/S0969-2126(98)00156-7

実験手法

X-RAY DIFFRACTION (2.45 Å)