1QOL

STRUCTURE OF THE FMDV LEADER PROTEASE

Summary for 1QOL

Related1QMY 1QQP
DescriptorPROTEASE (NONSTRUCTURAL PROTEIN P20A), 1,2-ETHANEDIOL, CHLORIDE ION (3 entities in total)
Functional Keywordshydrolase, sulfhydryl proteinase, picornaviral proteinase
Biological sourceFOOT-AND-MOUTH DISEASE VIRUS
Cellular locationProtein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B-1: Virion (Potential). Protein 3B-2: Virion (Potential). Protein 3B-3: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential) P03305
Total number of polymer chains8
Total molecular weight158526.33
Authors
Guarne, A.,Tormo, J.,Kirchweger, R.,Pfistermueller, D.,Skern, T.,Fita, I. (deposition date: 1999-11-13, release date: 2000-11-10, Last modification date: 2011-07-13)
Primary citation
Guarne, A.,Tormo, J.,Kirchweger, R.,Pfistermueller, D.,Fita, I.,Skern, T.
Structure of the Foot-and-Mouth Disease Virus Leader Protease: A Papain-Like Fold Adapted for Self-Processing and Eif4G Recognition.
Embo J., 17:7469-, 1998
PubMed: 9857201 (PDB entries with the same primary citation)
DOI: 10.1093/EMBOJ/17.24.7469
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.312283.7%4.3%0.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution