1QK2

WILD TYPE CEL6A WITH A NON-HYDROLYSABLE CELLOTETRAOSE

1QK2 の概要

• エントリーDOI: 10.2210/pdb1qk2/pdb
• 分子名称: CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: hydrolase, glycosidase, glycoprotein
• 由来する生物種: TRICHODERMA REESEI
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 82622.68

構造登録者

Zou, J.-Y.,Jones, T.A. (登録日: 1999-07-09, 公開日: 1999-09-18, 最終更新日: 2024-10-23)

主引用文献

Zou, J.-Y.,Kleywegt, G.J.,Stahlberg, J.,Driguez, H.,Nerinckx, W.,Claeyssens, M.,Koivula, A.,Teeri, T.T.,Jones, T.A.
Crystallographic Evidence for Substrate Ring Distortion and Protein Conformational Changes During Catalysis in Cellobiohydrolase Cel6A from Trichoderma Reesei
Structure, 7:1035-, 1999

PubMed Abstract: Cel6A is one of the two cellobiohydrolases produced by Trichoderma reesei. The catalytic core has a structure that is a variation of the classic TIM barrel. The active site is located inside a tunnel, the roof of which is formed mainly by a pair of loops.

PubMed: 10508787
DOI: 10.1016/S0969-2126(99)80171-3

実験手法

X-RAY DIFFRACTION (2 Å)