1QIB

CRYSTAL STRUCTURE OF GELATINASE A CATALYTIC DOMAIN

1QIB の概要

• エントリーDOI: 10.2210/pdb1qib/pdb
• 分子名称: 72 kDa type IV collagenase, ZINC ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: inhibitor, matrixin, matrix metalloproteinase-2 (mmp-2), gelatinase a, metzincin, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Isoform 1: Secreted, extracellular space, extracellular matrix. Isoform 2: Cytoplasm: P08253
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18208.91

構造登録者

Dhanaraj, V.,Williams, M.G.,Ye, Q.-Z.,Molina, F.,Johnson, L.L.,Ortwine, D.F.,Pavlovsky, A.,Rubin, J.R.,Skeean, R.W.,White, A.D.,Humblet, C.,Hupe, D.J.,Blundell, T.L. (登録日: 1999-06-11, 公開日: 1999-11-19, 最終更新日: 2023-12-27)

• 主引用文献: Dhanaraj, V.,Williams, M.G.,Ye, Q.-Z.,Molina, F.,Johnson, L.L.,Ortwine, D.F.,Pavlovsky, A.,Rubin, J.R.,Skeean, R.W.,White, A.D.,Humblet, C.,Hupe, D.J.,Blundell, T.L.; X-ray structure of gelatinase A catalytic domain complexed with a hydroxamate inhibitor; Croatica Chemica Acta, 72:575-591, 1999

実験手法

X-RAY DIFFRACTION (2.8 Å)