1QAJ

CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN

1QAJ の概要

• エントリーDOI: 10.2210/pdb1qaj/pdb
• 分子名称: DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3'), REVERSE TRANSCRIPTASE (3 entities in total)
• 機能のキーワード: protein-dna complex, polymerase, reverse transcriptase, moloney murine leukemia virus, transferase-dna complex, transferase/dna
• 由来する生物種: Moloney murine leukemia virus
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor (Potential). Matrix protein p15: Virion (Potential). Capsid protein p30: Virion (Potential). Nucleocapsid protein p10: Virion (Potential): P03355
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 63548.74

構造登録者

Najmudin, S.,Cote, M.,Sun, D.,Yohannan, S.,Montano, S.P.,Gu, J.,Georgiadis, M.M. (登録日: 1999-03-18, 公開日: 2000-04-02, 最終更新日: 2024-02-14)

• 主引用文献: Najmudin, S.,Cote, M.L.,Sun, D.,Yohannan, S.,Montano, S.P.,Gu, J.,Georgiadis, M.M.; Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.; J.Mol.Biol., 296:613-632, 2000; PubMed: 10669612; DOI: 10.1006/jmbi.1999.3477

実験手法

X-RAY DIFFRACTION (2.3 Å)