1QAF

THE ACTIVE SITE BASE CONTROLS COFACTOR REACTIVITY IN ESCHERICHIA COLI AMINE OXIDASE : X-RAY CRYSTALLOGRAPHIC STUDIES WITH MUTATIONAL VARIANTS

Summary for 1QAF

• Entry DOI: 10.2210/pdb1qaf/pdb
• Descriptor: PROTEIN (COPPER AMINE OXIDASE), COPPER (II) ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: catalytic domain mainly anti-parallel beta sheet, three peripheral alpha-beta domains, oxidoreductase
• Biological source: Escherichia coli
• Cellular location: Periplasm: P46883
• Total number of polymer chains: 2
• Total formula weight: 161977.75

Authors

Murray, J.M.,Wilmot, C.M.,Saysell, C.G.,Jaeger, J.,Knowles, P.F.,Phillips, S.E.,McPherson, M.J. (deposition date: 1999-03-11, release date: 1999-08-23, Last modification date: 2023-08-16)

• Primary citation: Murray, J.M.,Saysell, C.G.,Wilmot, C.M.,Tambyrajah, W.S.,Jaeger, J.,Knowles, P.F.,Phillips, S.E.,McPherson, M.J.; The active site base controls cofactor reactivity in Escherichia coli amine oxidase: x-ray crystallographic studies with mutational variants.; Biochemistry, 38:8217-8227, 1999; PubMed: 10387067; DOI: 10.1021/bi9900469

Experimental method

X-RAY DIFFRACTION (2.2 Å)