1Q7A

Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution

1Q7A の概要

• エントリーDOI: 10.2210/pdb1q7a/pdb
• 関連するPDBエントリー: 1CL5 1OYF
• 分子名称: Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE, ... (5 entities in total)
• 機能のキーワード: phospholipase a2, venom, antiinflammatory compound, hydrolase
• 由来する生物種: Daboia russellii pulchella
• 細胞内の位置: Secreted: P59071
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14178.31

構造登録者

Singh, N.,Jabeen, T.,Sharma, S.,Singh, T.P. (登録日: 2003-08-17, 公開日: 2004-05-11, 最終更新日: 2023-08-16)

• 主引用文献: Singh, N.,Jabeen, T.,Somvanshi, R.K.,Sharma, S.,Dey, S.,Singh, T.P.; Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution.; Biochemistry, 43:14577-14583, 2004; PubMed: 15544328; DOI: 10.1021/bi0483561

実験手法

X-RAY DIFFRACTION (1.6 Å)