1Q6Y

Hypothetical protein YfdW from E. coli bound to Coenzyme A

1Q6Y の概要

• エントリーDOI: 10.2210/pdb1q6y/pdb
• 関連するPDBエントリー: 1PQY
• 分子名称: Hypothetical protein yfdW, COENZYME A, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• 機能のキーワード: intertwined dimer, structural genomics, coenzyme a, psi, protein structure initiative, new york sgx research center for structural genomics, nysgxrc, transferase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48831.14

構造登録者

Gogos, A.,Gorman, J.,Shapiro, L.,Burley, S.K.,New York SGX Research Center for Structural Genomics (NYSGXRC) (登録日: 2003-08-14, 公開日: 2003-09-30, 最終更新日: 2023-08-16)

主引用文献

Gogos, A.,Gorman, J.,Shapiro, L.
Structure of Escherichia coli YfdW, a type III CoA transferase.
Acta Crystallogr.,Sect.D, 60:507-511, 2004

PubMed Abstract: Crystal structures are reported for free and coenzyme A (CoA) bound forms of the YfdW protein from Escherichia coli, a representative type III CoA transferase. The structures reveal a two-domain protomer with interdomain connections forming a ring-like structure with a large central hole. Two protomers associate to form a highly intertwined dimer in which the hole of each ring is filled by the partner molecule. Each protomer binds a single CoA molecule and these CoA-binding sites are distant from one another in the dimer.

PubMed: 14993676
DOI: 10.1107/S0907444904000034

実験手法

X-RAY DIFFRACTION (1.99 Å)