1Q4G

2.0 Angstrom Crystal Structure of Ovine Prostaglandin H2 Synthase-1, in complex with alpha-methyl-4-biphenylacetic acid

1Q4G の概要

• エントリーDOI: 10.2210/pdb1q4g/pdb
• 関連するPDBエントリー: 1CQE 1EQG 1EQH 1HT5 1HT8 1PRH
• 分子名称: Prostaglandin G/H synthase 1, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: cyclooxygenase, non-steroidal anti-inflammatory drug, peroxidase, prostaglandin synthase, egf-like domain, membrane binding domain, oxidoreductase
• 由来する生物種: Ovis aries (sheep)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 136101.03

構造登録者

Gupta, K.,Selinksy, B.S.,Kaub, C.J.,Katz, A.K.,Loll, P.J. (登録日: 2003-08-03, 公開日: 2004-01-06, 最終更新日: 2023-08-16)

• 主引用文献: Gupta, K.,Selinsky, B.S.,Kaub, C.J.,Katz, A.K.,Loll, P.J.; The 2.0A Resolution Crystal Structure of Prostaglandin H(2) Synthase-1: Structural Insights into an Unusual Peroxidase; J.Mol.Biol., 335:503-518, 2004; PubMed: 14672659; DOI: 10.1016/j.jmb.2003.10.073

実験手法

X-RAY DIFFRACTION (2 Å)