1Q3D

GSK-3 Beta complexed with Staurosporine

Summary for 1Q3D

• Entry DOI: 10.2210/pdb1q3d/pdb
• Related: 1PYX
• Descriptor: GLYCOGEN SYNTHASE KINASE-3 BETA, STAUROSPORINE (3 entities in total)
• Functional Keywords: kinase, insulin pathway, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P49841
• Total number of polymer chains: 2
• Total formula weight: 95096.01

Authors

Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M. (deposition date: 2003-07-29, release date: 2003-10-21, Last modification date: 2023-08-16)

• Primary citation: Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M.; Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors; J.Mol.Biol., 333:393-407, 2003; PubMed: 14529625; DOI: 10.1016/j.jmb.2003.08.031

Experimental method

X-RAY DIFFRACTION (2.2 Å)