1PZJ

Cholera Toxin B-Pentamer Complexed With Nitrophenyl Galactoside 5

Summary for 1PZJ

Entry DOI	10.2210/pdb1pzj/pdb
Related	1PZI 1PZK
Descriptor	Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-BETA-BENZAMIDE, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-ALPHA-BENZAMIDE, ... (4 entities in total)
Functional Keywords	pentamer, monovalent, toxin, inhibitor, cholera
Biological source	Vibrio cholerae
Total number of polymer chains	5
Total formula weight	60754.17
Authors	Mitchell, D.D.,Pickens, J.C.,Korotkov, K.,Fan, E.,Hol, W.G.J. (deposition date: 2003-07-11, release date: 2004-03-09, Last modification date: 2023-08-16)
Primary citation	Mitchell, D.D.,Pickens, J.C.,Korotkov, K.,Fan, E.,Hol, W.G.J. 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies Bioorg.Med.Chem., 12:907-920, 2004 Cited by PubMed: 14980603 DOI: 10.1016/j.bmc.2003.12.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation