1PYW

Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)

1PYW の概要

• エントリーDOI: 10.2210/pdb1pyw/pdb
• 関連するPDBエントリー: 1DLH 1KLU
• 分子名称: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR-1 beta chain, 9-residue influenza virus hemagglutinin related peptide FVKQNA(MAA)AL, ... (5 entities in total)
• 機能のキーワード: mhc class ii, major histocompatibility protein complex, hla-dr1, influenza, hemagglutinin, superantigen, antigen, immune system-protein binding-toxin complex, immune system/protein binding/toxin
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: P01903
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 71959.82

構造登録者

Zavala-Ruiz, Z.,Sundberg, E.J.,Stone, J.D.,DeOliveira, D.B.,Chan, I.C.,Svendsen, J.,Mariuzza, R.A.,Stern, L.J. (登録日: 2003-07-09, 公開日: 2003-12-09, 最終更新日: 2023-08-16)

• 主引用文献: Zavala-Ruiz, Z.,Sundberg, E.J.,Stone, J.D.,DeOliveira, D.B.,Chan, I.C.,Svendsen, J.,Mariuzza, R.A.,Stern, L.J.; Exploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1; J.Biol.Chem., 278:44904-44912, 2003; PubMed: 12952957; DOI: 10.1074/jbc.M307652200

実験手法

X-RAY DIFFRACTION (2.1 Å)