1PY1

Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide

Summary for 1PY1

Entry DOI	10.2210/pdb1py1/pdb
Descriptor	ADP-ribosylation factor binding protein GGA1, Beta-secretase (3 entities in total)
Functional Keywords	vhs domain of gga1, beta-secretase, protein-peptide complex, super helix, protein transport
Biological source	Homo sapiens (human) More
Cellular location	Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein: Q9UJY5 Membrane; Single-pass type I membrane protein: P56817
Total number of polymer chains	8
Total formula weight	75654.26
Authors	Zhu, G.,Zhang, X.C. (deposition date: 2003-07-07, release date: 2003-11-04, Last modification date: 2023-08-16)
Primary citation	He, X.,Zhu, G.,Koelsch, G.,Rodgers, K.,Zhang, X.C.,Tang, J. Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins. Biochemistry, 42:12174-12180, 2003 Cited by PubMed: 14567678 DOI: 10.1021/bi035199h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation