1PY1

Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide

1PY1 の概要

• エントリーDOI: 10.2210/pdb1py1/pdb
• 分子名称: ADP-ribosylation factor binding protein GGA1, Beta-secretase (3 entities in total)
• 機能のキーワード: vhs domain of gga1, beta-secretase, protein-peptide complex, super helix, protein transport
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein: Q9UJY5; Membrane; Single-pass type I membrane protein: P56817
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 75654.26

構造登録者

Zhu, G.,Zhang, X.C. (登録日: 2003-07-07, 公開日: 2003-11-04, 最終更新日: 2023-08-16)

• 主引用文献: He, X.,Zhu, G.,Koelsch, G.,Rodgers, K.,Zhang, X.C.,Tang, J.; Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins.; Biochemistry, 42:12174-12180, 2003; PubMed: 14567678; DOI: 10.1021/bi035199h

実験手法

X-RAY DIFFRACTION (2.6 Å)