1PWA

Crystal structure of Fibroblast Growth Factor 19

1PWA の概要

• エントリーDOI: 10.2210/pdb1pwa/pdb
• 分子名称: Fibroblast growth factor-19, SULFATE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• 機能のキーワード: beta trefoil, disulphide bonds, hormone-growth factor complex, hormone/growth factor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: O95750
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18426.97

構造登録者

Harmer, N.J.,Pellegrini, L.,Chirgadze, D.,Fernandez-Recio, J.,Blundell, T.L. (登録日: 2003-07-01, 公開日: 2004-01-27, 最終更新日: 2023-08-16)

• 主引用文献: Harmer, N.J.,Pellegrini, L.,Chirgadze, D.,Fernandez-Recio, J.,Blundell, T.L.; The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.; Biochemistry, 43:629-640, 2004; PubMed: 14730967; DOI: 10.1021/bi035320k

実験手法

X-RAY DIFFRACTION (1.3 Å)