1PTX

CRYSTAL STRUCTURE OF TOXIN II FROM THE SCORPION ANDROCTONUS AUSTRALIS HECTOR REFINED AT 1.3 ANGSTROMS RESOLUTION

1PTX の概要

• エントリーDOI: 10.2210/pdb1ptx/pdb
• 分子名称: SCORPION TOXIN II (2 entities in total)
• 機能のキーワード: toxin
• 由来する生物種: Androctonus australis (Sahara scorpion)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 7262.17

構造登録者

Fontecilla-Camps, J.C.,Housset, D. (登録日: 1994-09-02, 公開日: 1995-01-26, 最終更新日: 2024-10-16)

主引用文献

Housset, D.,Habersetzer-Rochat, C.,Astier, J.P.,Fontecilla-Camps, J.C.
Crystal structure of toxin II from the scorpion Androctonus australis Hector refined at 1.3 A resolution.
J.Mol.Biol., 238:88-103, 1994

PubMed Abstract: The crystal structure of toxin II from the scorpion Androctonus australis Hector has been refined at 1.3 A resolution using restrained least-squares methods. The final R-factor is 0.148 for the 13,619 reflections between 7.0 A and 1.3 A resolution with F > 2.5 sigma (F) and the bond length standard deviation from ideality is 0.017 A. Although minor changes have been introduced relative to the model previously refined at 1.8 A resolution, the use of higher-resolution data has allowed the modelling of some discrete disorder. Thus, three residues (including a disulphide bridge) have been built with multiple conformations. Occupancies were refined for the 106 solvent molecules included in the model, nine of them with explicit multiple sites. There is well-defined electron density for some of the protein hydrogen atoms in the final difference Fourier map. A detailed description of the toxin structure is presented, along with a comparison with the high-resolution structure of the related variant-3 scorpion toxin.

PubMed: 8145259
DOI: 10.1006/jmbi.1994.1270

実験手法

X-RAY DIFFRACTION (1.3 Å)