1PTT
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING TETRA-PEPTIDE (AC-DEPYL-NH2)
Summary for 1PTT
| Entry DOI | 10.2210/pdb1ptt/pdb |
| Descriptor | PROTEIN TYROSINE PHOSPHATASE 1B, PHOSPHOTYROSINE-CONTAINING TETRA-PEPTIDE (2 entities in total) |
| Functional Keywords | hydrolase, acetylation, phosphorylation, complex (hydrolase-peptide) complex, complex (hydrolase/peptide) |
| Biological source | Homo sapiens (human) |
| Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P18031 |
| Total number of polymer chains | 2 |
| Total formula weight | 38008.16 |
| Authors | Barford, D.,Jia, Z. (deposition date: 1995-04-21, release date: 1996-08-01, Last modification date: 2021-11-03) |
| Primary citation | Jia, Z.,Barford, D.,Flint, A.J.,Tonks, N.K. Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268:1754-1758, 1995 Cited by PubMed: 7540771PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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