1PT9

Crystal Structure Analysis of the DIII Component of Transhydrogenase with a Thio-Nicotinamide Nucleotide Analogue

Summary for 1PT9

Entry DOI	10.2210/pdb1pt9/pdb
Related	1PTJ
Descriptor	NAD(P) transhydrogenase, mitochondrial, SULFATE ION, 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	transhydrogenase, thio-nicotinamide, mitochondria, proton translocation, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion inner membrane ; Multi-pass membrane protein ; Matrix side : Q13423
Total number of polymer chains	2
Total formula weight	46458.56
Authors	Singh, A.,Venning, J.D.,Quirk, P.G.,van Boxel, G.I.,Rodrigues, D.J.,White, S.A.,Jackson, J.B. (deposition date: 2003-06-23, release date: 2003-10-07, Last modification date: 2023-08-16)
Primary citation	Singh, A.,Venning, J.D.,Quirk, P.G.,Van Boxel, G.I.,Rodrigues, D.J.,White, S.A.,Jackson, J.B. Interactions between transhydrogenase and thio-nicotinamide analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation J.Biol.Chem., 278:33208-33216, 2003 Cited by PubMed: 12791694 DOI: 10.1074/jbc.M303061200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.42 Å)

Structure validation