1PT9

Crystal Structure Analysis of the DIII Component of Transhydrogenase with a Thio-Nicotinamide Nucleotide Analogue

1PT9 の概要

• エントリーDOI: 10.2210/pdb1pt9/pdb
• 関連するPDBエントリー: 1PTJ
• 分子名称: NAD(P) transhydrogenase, mitochondrial, SULFATE ION, 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: transhydrogenase, thio-nicotinamide, mitochondria, proton translocation, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion inner membrane ; Multi-pass membrane protein ; Matrix side : Q13423
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46458.56

構造登録者

Singh, A.,Venning, J.D.,Quirk, P.G.,van Boxel, G.I.,Rodrigues, D.J.,White, S.A.,Jackson, J.B. (登録日: 2003-06-23, 公開日: 2003-10-07, 最終更新日: 2023-08-16)

• 主引用文献: Singh, A.,Venning, J.D.,Quirk, P.G.,Van Boxel, G.I.,Rodrigues, D.J.,White, S.A.,Jackson, J.B.; Interactions between transhydrogenase and thio-nicotinamide analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation; J.Biol.Chem., 278:33208-33216, 2003; PubMed: 12791694; DOI: 10.1074/jbc.M303061200

実験手法

X-RAY DIFFRACTION (2.42 Å)