1PPH

GEOMETRY OF BINDING OF THE NALPHA-TOSYLATED PIPERIDIDES OF M-AMIDINO-, P-AMIDINO-AND P-GUANIDINO PHENYLALANINE TO THROMBIN AND TRYPSIN: X-RAY CRYSTAL STRUCTURES OF THEIR TRYPSIN COMPLEXES AND MODELING OF THEIR THROMBIN COMPLEXES

1PPH の概要

• エントリーDOI: 10.2210/pdb1pph/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000374
• 分子名称: TRYPSIN, CALCIUM ION, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Sus scrofa (pig)
• 細胞内の位置: Secreted, extracellular space: P00760
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23888.98

構造登録者

Bode, W.,Turk, D. (登録日: 1991-10-24, 公開日: 1994-01-31, 最終更新日: 2012-12-12)

• 主引用文献: Turk, D.,Sturzebecher, J.,Bode, W.; Geometry of binding of the N alpha-tosylated piperidides of m-amidino-, p-amidino- and p-guanidino phenylalanine to thrombin and trypsin. X-ray crystal structures of their trypsin complexes and modeling of their thrombin complexes.; FEBS Lett., 287:133-138, 1991; PubMed: 1879520; DOI: 10.1016/0014-5793(91)80033-Y

実験手法

X-RAY DIFFRACTION (1.9 Å)