1POV

ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION

1POV の概要

• エントリーDOI: 10.2210/pdb1pov/pdb
• 分子名称: POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), MYRISTIC ACID, SPHINGOSINE, ... (6 entities in total)
• 機能のキーワード: picornavirus, icosahedral virus, virus
• 由来する生物種: Human poliovirus 1; 詳細
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300 P03300 P03300
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 98014.72

構造登録者

Basavappa, R.,Filman, D.J.,Hogle, J.M. (登録日: 1995-08-10, 公開日: 1995-12-07, 最終更新日: 2023-04-19)

• 主引用文献: Basavappa, R.,Syed, R.,Flore, O.,Icenogle, J.P.,Filman, D.J.,Hogle, J.M.; Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution.; Protein Sci., 3:1651-1669, 1994; PubMed: 7849583

実験手法

X-RAY DIFFRACTION (2.8 Å)