1PMU
The crystal structure of JNK3 in complex with a phenantroline inhibitor
Summary for 1PMU
Entry DOI | 10.2210/pdb1pmu/pdb |
Related | 1PMN 1PMQ 1PMV |
Descriptor | Mitogen-activated protein kinase 10, CHLORIDE ION, 9-(4-HYDROXYPHENYL)-2,7-PHENANTHROLINE, ... (4 entities in total) |
Functional Keywords | map kinase, apoptosis, inhibition, selectivity, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P53779 |
Total number of polymer chains | 1 |
Total formula weight | 42309.40 |
Authors | Scapin, G.,Patel, S.B.,Lisnock, J.,Becker, J.W.,LoGrasso, P.V. (deposition date: 2003-06-11, release date: 2003-09-09, Last modification date: 2023-08-16) |
Primary citation | Scapin, G.,Patel, S.B.,Lisnock, J.,Becker, J.W.,LoGrasso, P.V. The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity Chem.Biol., 10:705-712, 2003 Cited by PubMed: 12954329DOI: 10.1016/S1074-5521(03)00159-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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