1PM7

RmlC (dTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE)STRUCTURE FROM MYCOBACTERIUM TUBERCULOSIS AND INHIBITOR DESIGN. THE APO STRUCTURE.

1PM7 の概要

• エントリーDOI: 10.2210/pdb1pm7/pdb
• 分子名称: RFBC, ACETATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: rmlc, beta barrel, main beta sheet structure, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, isomerase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44976.17

構造登録者

Dong, C.,Naismith, J.H.,TB Structural Genomics Consortium (TBSGC) (登録日: 2003-06-10, 公開日: 2003-12-09, 最終更新日: 2024-02-14)

• 主引用文献: Babaoglu, K.,Page, M.A.,Jones, V.C.,McNeil, M.R.,Dong, C.,Naismith, J.H.,Lee, R.E.; Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis.; Bioorg.Med.Chem.Lett., 13:3227-3230, 2003; PubMed: 12951098; DOI: 10.1016/S0960-894X(03)00673-5

実験手法

X-RAY DIFFRACTION (2.2 Å)