1PKM

THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS

1PKM の概要

• エントリーDOI: 10.2210/pdb1pkm/pdb
• 分子名称: M1 PYRUVATE KINASE (1 entity in total)
• 機能のキーワード: pyruvate kinase, kinase
• 由来する生物種: Felis catus (domestic cat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57997.85

構造登録者

Allen, S.C.,Muirhead, H. (登録日: 1995-07-13, 公開日: 1995-10-15, 最終更新日: 2024-02-14)

主引用文献

Allen, S.C.,Muirhead, H.
Refined three-dimensional structure of cat-muscle (M1) pyruvate kinase at a resolution of 2.6 A.
Acta Crystallogr.,Sect.D, 52:499-504, 1996

PubMed Abstract: The three-dimensional structure of cat-muscle pyoruvate kinase has been refined at a resolution of 2.6 A. The details of the structure permit interpretation of the original heavy-atom studies and give insight into the importance of conserved residues in pyruvate kinases and the allosteric behaviour of the enzyme. There are a small number of essential residues which determine the relative orientations of domains and the precise nature of intersubunit contacts. Arginine residues are particularly important.

PubMed: 15299671
DOI: 10.1107/S0907444995016040

実験手法

X-RAY DIFFRACTION (2.6 Å)