1PKD

THE CRYSTAL STRUCTURE OF UCN-01 IN COMPLEX WITH PHOSPHO-CDK2/CYCLIN A

Summary for 1PKD

Related1QMZ
DescriptorCell division protein kinase 2, Cyclin A2, 7-HYDROXYSTAUROSPORINE, ... (4 entities in total)
Functional Keywordsprotein kinase-drug complex, transferase-cell cycle complex, transferase/cell cycle
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, microtubule organizing center, centrosome P24941
Nucleus  P20248
Total number of polymer chains4
Total molecular weight127960.04
Authors
Johnson, L.N.,De Moliner, E.,Brown, N.R.,Song, H. (deposition date: 2003-06-05, release date: 2003-06-24, Last modification date: 2018-01-31)
Primary citation
Johnson, L.N.,De Moliner, E.,Brown, N.R.,Song, H.
The Crystal Structure of UCN-01 in Complex with Phospho-CDK2/Cyclin A
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.259100.8%10.1%7.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report