1PJ4
Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, ATP, Mn++, and allosteric activator fumarate.
Summary for 1PJ4
Entry DOI | 10.2210/pdb1pj4/pdb |
Related | 1PJ2 1PJ3 |
Descriptor | NAD-dependent malic enzyme, mitochondrial, D-MALATE, MANGANESE (II) ION, ... (6 entities in total) |
Functional Keywords | oxidative decarboxylase, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P23368 |
Total number of polymer chains | 4 |
Total formula weight | 260850.51 |
Authors | |
Primary citation | Tao, X.,Yang, Z.,Tong, L. Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure, 11:1141-1150, 2003 Cited by PubMed: 12962632DOI: 10.1016/S0969-2126(03)00168-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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