1PIV
BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14
Summary for 1PIV
Entry DOI | 10.2210/pdb1piv/pdb |
Descriptor | POLIOVIRUS TYPE 3 (SUBUNIT VP1), POLIOVIRUS TYPE 3 (SUBUNIT VP2), POLIOVIRUS TYPE 3 (SUBUNIT VP3), ... (7 entities in total) |
Functional Keywords | virus, icosahedral virus |
Biological source | Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B) More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03302 P03302 P03302 P03302 |
Total number of polymer chains | 5 |
Total formula weight | 98449.06 |
Authors | Hiremath, C.N.,Grant, R.A.,Filman, D.J.,Hogle, J.M. (deposition date: 1995-02-02, release date: 1995-06-03, Last modification date: 2024-06-05) |
Primary citation | Hiremath, C.N.,Grant, R.A.,Filman, D.J.,Hogle, J.M. Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14. Acta Crystallogr.,Sect.D, 51:473-489, 1995 Cited by PubMed: 15299834DOI: 10.1107/S090744499401084X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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