1PI5
Structure of N289A mutant of AmpC in complex with SM2, carboxyphenylglycylboronic acid bearing the cephalothin R1 side chain
Summary for 1PI5
Entry DOI | 10.2210/pdb1pi5/pdb |
Related | 1MXO 1MY8 |
Descriptor | Beta-lactamase, PHOSPHATE ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | enzyme inhibitor complex, beta-lactamase, hydrolase |
Biological source | Escherichia coli |
Cellular location | Periplasm: P00811 |
Total number of polymer chains | 2 |
Total formula weight | 80220.39 |
Authors | Roth, T.A.,Minasov, G.,Focia, P.J.,Shoichet, B.K. (deposition date: 2003-05-29, release date: 2004-02-24, Last modification date: 2023-08-16) |
Primary citation | Roth, T.A.,Minasov, G.,Morandi, S.,Prati, F.,Shoichet, B.K. Thermodynamic cycle analysis and inhibitor design against beta-lactamase. Biochemistry, 42:14483-14491, 2003 Cited by PubMed: 14661960DOI: 10.1021/bi035054a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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