1PF7
CRYSTAL STRUCTURE OF HUMAN PNP COMPLEXED WITH IMMUCILLIN H
Summary for 1PF7
Entry DOI | 10.2210/pdb1pf7/pdb |
Related | 1M73 |
Descriptor | PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, ... (4 entities in total) |
Functional Keywords | purine nucleoside phosphorylase, drug design, synchrotron, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton (By similarity): P00491 |
Total number of polymer chains | 1 |
Total formula weight | 32739.32 |
Authors | De Azevedo Jr., W.F.,Canduri, F.,Dos Santos, D.M.,Pereira, J.H.,Dias, M.V.B.,Silva, R.G.,Mendes, M.A.,Palma, M.S.,Basso, L.A.,Santos, D.S. (deposition date: 2003-05-24, release date: 2004-06-01, Last modification date: 2023-09-20) |
Primary citation | De Azevedo Jr., W.F.,Canduri, F.,Dos Santos, D.M.,Pereira, J.H.,Dias, M.V.B.,Silva, R.G.,Mendes, M.A.,Palma, M.S.,Basso, L.A.,Santos, D.S. Structural basis for inhibition of human PNP by immucillin-H Biochem.Biophys.Res.Commun., 309:917-922, 2003 Cited by PubMed: 13679061DOI: 10.1016/j.bbrc.2003.08.094 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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