1PDB
Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase
Summary for 1PDB
| Entry DOI | 10.2210/pdb1pdb/pdb |
| Related | 1PD8 1PD9 |
| Descriptor | Dihydrofolate reductase (2 entities in total) |
| Functional Keywords | human dihydrofolate reductase inhibitor complexes, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 21349.53 |
| Authors | Cody, V.,Luft, J.R.,Pangborn, W.,Gangjee, A. (deposition date: 2003-05-19, release date: 2003-12-09, Last modification date: 2023-08-16) |
| Primary citation | Cody, V.,Luft, J.R.,Pangborn, W.,Gangjee, A. Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59:1603-1609, 2003 Cited by PubMed: 12925791DOI: 10.1107/S0907444903014963 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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