1PCW
Aquifex aeolicus KDO8PS in complex with cadmium and APP, a bisubstrate inhibitor
Summary for 1PCW
Entry DOI | 10.2210/pdb1pcw/pdb |
Related | 1JCX |
Descriptor | 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, 1-DEOXY-6-O-PHOSPHONO-1-[(PHOSPHONOMETHYL)AMINO]-L-THREO-HEXITOL, ... (4 entities in total) |
Functional Keywords | beta(8)/alpha(8) barrel, lyase |
Biological source | Aquifex aeolicus |
Cellular location | Cytoplasm (By similarity): O66496 |
Total number of polymer chains | 2 |
Total formula weight | 60483.98 |
Authors | Xu, X.,Wang, J.,Grison, C.,Petek, S.,Coutrot, P.,Birck, M.,Woodard, R.W.,Gatti, D.L. (deposition date: 2003-05-17, release date: 2004-02-17, Last modification date: 2023-08-16) |
Primary citation | Xu, X.,Wang, J.,Grison, C.,Petek, S.,Coutrot, P.,Birck, M.R.,Woodard, R.W.,Gatti, D.L. Structure-Based Design of Novel Inhibitors of 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase. Drug DES.DISCOVERY, 18:91-99, 2003 Cited by PubMed: 14675946PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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