1P9U

Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs

Summary for 1P9U

• Entry DOI: 10.2210/pdb1p9u/pdb
• Related: 1LVO 1P9S 1P9T
• Related PRD ID: PRD_000457
• Descriptor: putative coronavirus nsp2 (3CL-PRO), PHQ-VNSTLQ-CHLOROMETHYLKETONE INHIBITOR, SULFATE ION, ... (5 entities in total)
• Functional Keywords: sars-cov, hcov, tgev, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Transmissible gastroenteritis virus; More
• Total number of polymer chains: 8
• Total formula weight: 203210.13

Authors

Anand, K.,Ziebuhr, J.,Wadhwani, P.,Mesters, J.R.,Hilgenfeld, R. (deposition date: 2003-05-12, release date: 2003-05-20, Last modification date: 2017-10-11)

• Primary citation: Anand, K.,Ziebuhr, J.,Wadhwani, P.,Mesters, J.R.,Hilgenfeld, R.; Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs; Science, 300:1763-1767, 2003; PubMed: 12746549; DOI: 10.1126/science.1085658

Experimental method

X-RAY DIFFRACTION (2.37 Å)