1P9L

Structure of M. tuberculosis dihydrodipicolinate reductase in complex with NADH and 2,6 PDC

1P9L の概要

• エントリーDOI: 10.2210/pdb1p9l/pdb
• 関連するPDBエントリー: 1ARZ 1C3V 1DIH
• 分子名称: dihydrodipicolinate reductase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... (5 entities in total)
• 機能のキーワード: oxidoreductase, reductase, lysine biosynthesis, nadh binding specificity, tb structural genomics consortium, tbsgc, structural genomics, psi, protein structure initiative
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cytoplasm (By similarity): P72024
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53446.11

構造登録者

Cirilli, M.,Zheng, R.,Scapin, G.,Blanchard, J.S.,TB Structural Genomics Consortium (TBSGC) (登録日: 2003-05-12, 公開日: 2003-08-26, 最終更新日: 2023-08-16)

• 主引用文献: Cirilli, M.,Zheng, R.,Scapin, G.,Blanchard, J.S.; The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity.; Biochemistry, 42:10644-10650, 2003; PubMed: 12962488; DOI: 10.1021/bi030044v

実験手法

X-RAY DIFFRACTION (2.3 Å)